2014/05/09 by Mohammad Asif, Asif, Mohammad
Chemistry · Computer Science · #Computational Drug Discovery Methods #Heterocyclic compounds #Multicomponent Synthesis of Heterocycles #Synthesis and biological activity #biological activities. #oxadiazole #thiadiazole
paper · doi:10.48317/imist.prsm/morjchem-v2i2.1899
openalex publication_date 2014/05/09 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/15
In the last few years, heterocyclic compounds have attracted strong interest and a lot of work has been done on oxadiazole and thiadiazole ring. Oxadiazole and thiadiazole a five member heterocyclic nucleus has attracted a wide attention of the chemist in search for the new therapeutic agents. Various different oxadiazole and thiadiazole compounds have been prepared and possess useful pharmacological activities. Both oxadiazole and thiadiazole derivatives possess a wide range of pharmacological activities such as anticancer, anticonvulsant, antimicrobial, anti-inflammatory, antioxidant, antitubercular, antimalarial, antinociceptive etc. This review contains various pharmacological activities of oxadiazole and thiadiazole derivatives and it is the milestone for the new research towards oxadiazole and thiadiazole moiety.