2002/06/20 by Brian Ingalls, Brian P. Ingalls, Ingalls, Brian P. +2
Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · #Biological Physics (physics.bio-ph) #FOS: Biological sciences #FOS: Physical sciences #Gene Regulatory Network Analysis #Microbial Metabolic Engineering and Bioproduction #Photosynthetic Processes and Mechanisms #Quantitative Biology (q-bio) #physics.bio-ph #q-bio
paper · pdf · doi:10.48550/arxiv.physics/0206075
23 pages, 13 figures
arxiv created 2002/06/20 · openalex publication_date 2002/06/20 · arxiv updated 2009/12/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
A sensitivity analysis of general stoichiometric networks is considered. The results are presented as a generalization of Metabolic Control Analysis, which has been concerned primarily with system sensitivities at steady state. An expression for time-varying sensitivity coefficients is given, and the Summation and Connectivity Theorems are generalized. The results are compared to previous treatments. The analysis is accompanied by a discussion of the computation of the sensitivity coefficients and an application to a model of phototransduction.