2003/10/17 by Michael R. King, King, Michael R., Aimee D. Ruscio +5
Biochemistry, Genetics and Molecular Biology · Medicine · Physics and Astronomy · #Biological Physics (physics.bio-ph) #Cardiac and Coronary Surgery Techniques #Cell Adhesion Molecules Research #Cell Behavior (q-bio.CB) #FOS: Biological sciences #FOS: Physical sciences #Fluid Dynamics (physics.flu-dyn) #Platelet Disorders and Treatments #physics.bio-ph #physics.flu-dyn #q-bio.CB
paper · pdf · doi:10.48550/arxiv.physics/0310082
9 pages, 2 figures, submitted as Brief Report to Phys. Rev. E
arxiv created 2003/10/17 · openalex publication_date 2003/10/17 · arxiv updated 2009/12/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
We have characterized the two-dimensional spatial dependence of the hydrodynamic interactions between two adhesively rolling leukocytes in a live venule in the mouse cremaster muscle. Two rolling leukocytes were observed to slow each other down when rolling together in close proximity, due to mutual sheltering from the external blood flow in the vessel lumen. These results are in agreement with a previous study of leukocyte rolling interactions using carbohydrate-coated beads in a parallel-plate flow chamber and a detailed computer model of adhesion in a multicellular environment.