2009/01/12 by Wojciech Waga, Marta Zawierta, Waga, Wojciech +6
Biochemistry, Genetics and Molecular Biology · Computer Science · Mathematics · Social Sciences · #Artificial intelligence #Biology #Computer science #Darwinism #Econometrics #Evolution and Genetic Dynamics #Evolutionary Algorithms and Applications #Evolutionary Game Theory and Cooperation #Evolutionary biology #FOS: Biological sciences #Genetics #Genomics (q-bio.GN) #Mathematics #Monte Carlo method #Negative selection #Physics #Populations and Evolution (q-bio.PE) #Selection (genetic algorithm) #Statistical physics #Statistics #q-bio.GN #q-bio.PE
paper · pdf · doi:10.48550/arxiv.0901.1361
published in arXiv (Cornell University) (Cornell University) · 32 pages, 19 figures
arxiv created 2009/01/12 · openalex publication_date 2009/01/12 · arxiv updated 2009/12/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/05
Intragenomic recombination (crossover) is a very important evolutionary mechanism. The crossover events are not evenly distributed along the natural chromosomes. Monte Carlo simulations revealed that frequency of recombinations decides about the strategy of chromosomes' and genomes' evolution. In large panmictic populations, under high recombination rate the Darwinian purifying selection operates keeping the fraction of defective genes at the relatively low level. In small populations and under low recombination rate the strategy of complementing haplotypes seems to be more advantageous. Switching between the two strategies has a character of phase transition - it depends on inbreeding coefficient and crossover rate. The critical recombination rate depends also on the size of chromosome. It is also possible, that in one genome some chromosomes could be under complementing while some other under purifying selection. Such situation stabilizes genome evolution and reproduction strategy. It seems that this phenomenon can be responsible for the positive correlation between kinship and fecundity, recently found in the Islander population. When large population is forced to enter the complementing strategy, the phenomenon of sympatric speciation is observed.