2010/07/20 by S. Cebrat, Stanislaw Cebrat, Cebrat, Stanislaw +4
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Evolution and Genetic Dynamics #FOS: Biological sciences #Genetic diversity and population structure #Plant and animal studies #Populations and Evolution (q-bio.PE) #q-bio.PE
paper · pdf · doi:10.48550/arxiv.1007.3357
29 pages, 18 figures
arxiv created 2010/07/20 · openalex publication_date 2010/07/20 · arxiv updated 2010/07/21 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
We discuss two different ways of chromosomes' and genomes' evolution. Purifying selection dominates in large panmictic populations, where Mendelian law of independent gene assortment is valid. If the populations are small, recombination processes are not effective enough to ensure an independent assortment of linked genes and larger clusters of genes could be inherited as the genetic units. There are whole clusters of genes which tend to complement in such conditions instead of single pairs of alleles like in the case of purifying selection. Computer simulations have shown that switching in-between complementation and purification strategies has a character of a phase transition. This is also responsible for specific distribution of recombination events observed along eukaryotic chromosomes - higher recombination rate is observed in subtelomeric regions than in central parts of chromosomes - for sympatric speciation and probably for non-monotonous relation between reproduction potential and genetic distance between parents.