2023/06/28 by Seada, Samy Abo, van der Eerden, Anke W., Boon, Agnita J. W. +1
#FOS: Physical sciences #Medical Physics (physics.med-ph)
paper · doi:10.48550/arxiv.2306.16315
An optimized clinically feasible neuromelanin-MRI imaging protocol for visualising the SN and LC simultaneously using deep learning reconstruction is presented. We optimize flip-angle for optimal combined SN and LC depiction. We also experimented with combinations of anisotropic and isotropic in-plane resolution, partial vs full echoes and the number of averages. Phantom and in-vivo experiments on three healthy volunteers illustrate that high-resolution imaging combined with deep-learning denoising shows good depiction of the SN and LC with a clinically feasible sequence of around 7 minutes.