2017/02/14 by Dılek Nartop, Nartop, D., Özlem Özdemir +3
Chemistry · Medicine · #Antimicrobial activity. #Inorganic and Organometallic Chemistry #Metal complexes synthesis and properties #Potentiometry #Reduction #Synthesis and biological activity #Tautomerism #Unsymmetric Schiff base
paper · doi:10.48317/imist.prsm/morjchem-v5i4.7897
openalex publication_date 2017/02/14 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/01
Abstract A new unsymmetric Schiff base [(2OH)R-CH=N-(C6H4)-CH=N-R'(2OH) R=phenyl, R' = naphthyl] with its Fe(III) and Ni(II) complexes were synthesized by a two step method. Diimine Schiff base and its complexes were characterized by elemental analysis, mass spectra, IR, 1H/13C-NMR spectra, TGA analysis, electronic and magnetic measurements. The phenol-imine and keto-amine tautomerism of the unsymmetric Schiff base was investigated with NMR techniques and UV-visible spectra in different solvents. Also, the protonation constants of the ligand and the stability constants of its Ni(II) and Fe(III) complexes were determined potentiometrically in 1:1(v/v) ethanol-water mixture at an ionic strength of 0.5 mol·L-1 KCl and at 25.0 ± 0.1 oC. The antifungal, antimicrobial activities and the minimum inhibitory concentration (MIC) values of the compounds were evaluated against Escherichia coli (0157:H7), Micrococcus luteus (NRRLB 4975), Bacillus cereus (RSKK 863) and Candida albicans (ATCC 16231).