2010/12/14 by Md. Jahoor Alam, Alam, Md. Jahoor, Latika Bhayana +9
Biochemistry, Genetics and Molecular Biology · Chemistry · Physics and Astronomy · #Gene Regulatory Network Analysis #acm:34Nxx #msc:34Nxx #nlin.CD #physics.bio-ph #physics.comp-ph #q-bio.CB #stochastic dynamics and bifurcation #thermodynamics and calorimetric analyses
paper · pdf · doi:10.48550/arxiv.1012.2990
6 pages, 6 figures
arxiv created 2010/12/14 · arxiv updated 2010/12/15
The temporal behaviour of segmentation clock oscillations show phase synchrony via mean field like coupling of delta protein restricting to nearest neighbours only, in a configuration of cells arranged in a regular three dimensional array. We found the increase of amplitudes of oscillating dynamical variables of the cells as the activation rate of delta-notch signaling is increased, however, the frequencies of oscillations are decreased correspondingly. Our results show the phase transition from desynchronized to synchronized behaviour by identifying three regimes, namely, desynchronized, transition and synchronized regimes supported by various qualitative and quantitative measurements.