vix.ing · top · new · best · stats · spec

Holographic Digital Fourier Microscopy for Selective Imaging of Biological Tissue

2005/02/04 by Sergey Alexandrov, Sergey A. Alexandrov, Alexandrov, Sergey A. +9
Engineering · Physics and Astronomy · #Biological Physics (physics.bio-ph) #Digital Holography and Microscopy #FOS: Physical sciences #Optical Coherence Tomography Applications #Optics (physics.optics) #Photoacoustic and Ultrasonic Imaging #physics.bio-ph #physics.optics

paper · pdf · doi:10.48550/arxiv.physics/0502017

24 pages, 5 figures

arxiv created 2005/02/04 · openalex publication_date 2005/02/04 · arxiv updated 2009/12/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

This paper presents an application of digital Fourier holography for selective imaging of scatterers with different sizes in turbid media such as biological tissues. A combination of Fourier holography and high-resolution digital recording, digital Fourier microscopy (DFM) permits crucial flexibility in applying filtering to highlight scatterers of interest in the tissue. The high-resolution digital hologram is a result of the collation of Fourier holographic frames to form a large-size composite hologram. It is expected that DFM has an improved signal-to-noise ratio as compared to conventional direct digital imaging, e.g. phase microscopy, as applied to imaging of small-size objects. The demonstration of the Fourier filtering capacity of DFM using a biological phantom represents the main focus of this paper.

Related