2023/07/11 by Zhuxian Guo, Guo, Zhuxian, Qitong Wang +9
Computer Science · Medicine · Neuroscience · #AI in cancer detection #Brain Tumor Detection and Classification #Computer Vision and Pattern Recognition (cs.CV) #FOS: Computer and information sciences #FOS: Electrical engineering #Image and Video Processing (eess.IV) #Radiomics and Machine Learning in Medical Imaging #electronic engineering #information engineering
paper · pdf · doi:10.48550/arxiv.2307.05800
openalex publication_date 2023/07/11 · openalex created_date 2023/07/14 · openalex updated_date 2026/07/28
In digital histopathology, entire neoplasm segmentation on Whole Slide Image (WSI) of Hepatocellular Carcinoma (HCC) plays an important role, especially as a preprocessing filter to automatically exclude healthy tissue, in histological molecular correlations mining and other downstream histopathological tasks. The segmentation task remains challenging due to HCC's inherent high-heterogeneity and the lack of dependency learning in large field of view. In this article, we propose a novel deep learning architecture with a hierarchical Transformer encoder, HiTrans, to learn the global dependencies within expanded 4096×4096 WSI patches. HiTrans is designed to encode and decode the patches with larger reception fields and the learned global dependencies, compared to the state-of-the-art Fully Convolutional Neural networks (FCNN). Empirical evaluations verified that HiTrans leads to better segmentation performance by taking into account regional and global dependency information.