RIPK1 promotes inflammation and β-amyloid accumulation in Alzheimer’s disease

2017/10/02 by David C. Rubinsztein · 6 citations
Medicine · Neuroscience · #Alzheimer's disease research and treatments #Neuroinflammation and Neurodegeneration Mechanisms #Tryptophan and brain disorders

paper · pdf · doi:10.1073/pnas.1715241114

Abstract

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.

Cited by

• Inhibiting RIPK1 Limits Neuroinflammation and Alleviates Postoperative Cognitive Impairments in D-Galactose-Induced Aged Mice. [europepmc]
• Positive Feedback Loops in Alzheimer's Disease: The Alzheimer's Feedback Hypothesis. [europepmc]
• Overexpressed microRNA-494 represses RIPK1 to attenuate hippocampal neuron injury in epilepsy rats by inactivating the NF-κB signaling pathway. [europepmc]
• O -GlcNAcylation ameliorates the pathological manifestations of Alzheimer's disease by inhibiting necroptosis. [europepmc]
• RIPK1-Induced A1 Reactive Astrocytes in Brain in MPTP-Treated Murine Model of Parkinson's Disease. [europepmc]
• Die Hard: Necroptosis and its Impact on Age-Dependent Neuroinflammatory Diseases. [europepmc]

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