David C. Rubinsztein
- α-Synuclein Is Degraded by Both Autophagy and the Proteasome
2003/06/29 by Julie L. Webb, Brinda Ravikumar, Jane Atkins +3 · 39 citations
Medicine · Neuroscience · #Parkinson's Disease Mechanisms and Treatments #Autophagy in Disease and Therapy #Nerve injury and regeneration
- α-Synuclein impairs macroautophagy: implications for Parkinson’s disease
2010/09/20 by Ashley R. Winslow, Chien‐Wen Chen, Chien-Wen Chen +13 · 33 citations
Medicine · #Autophagy in Disease and Therapy #Parkinson's Disease Mechanisms and Treatments #Lysosomal Storage Disorders Research
- Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein
2006/12/21 by Sovan Sarkar, J. Eric Davies, Janet E. Davies +3 · 33 citations
Medicine · Neuroscience · #Autophagy in Disease and Therapy #Genetic Neurodegenerative Diseases #Parkinson's Disease Mechanisms and Treatments
- Lithium induces autophagy by inhibiting inositol monophosphatase
2005/09/26 by Sovan Sarkar, R. Andres Floto, R. Andrés Floto +7 · 29 citations
Medicine · #Autophagy in Disease and Therapy #Parkinson's Disease Mechanisms and Treatments #Lysosomal Storage Disorders Research
- Autophagy in Neuronal Development and Plasticity
2020/08/13 by Angeleen Fleming, David C. Rubinsztein · 2 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Autophagy in Disease and Therapy #Cannabis and Cannabinoid Research #Endoplasmic Reticulum Stress and Disease
- Mechanisms of cross‐talk between the ubiquitin‐proteasome and autophagy‐lysosome systems
2009/12/28 by Viktor I. Korolchuk, Fiona M. Menzies, David C. Rubinsztein · 25 citations
Medicine · Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Autophagy in Disease and Therapy #Ubiquitin and proteasome pathways #Toxoplasma gondii Research Studies
- Wild-type but not mutant huntingtin modulates the transcriptional activity of liver X receptors
2009/05/17 by Marie Futter, M Futter, H Diekmann +8 · 19 citations
Neuroscience · Biochemistry, Genetics and Molecular Biology · Medicine · #Genetic Neurodegenerative Diseases #Ubiquitin and proteasome pathways #Amyotrophic Lateral Sclerosis Research