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Discovery of Antimicrobial Phosphonopeptide Natural Products from Bacillus velezensis by Genome Mining

2023/05/31 by Jake Wilson, Jerry Cui, Toshiki Nakao +7 · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Genomics and Phylogenetic Studies #Microbial Natural Products and Biosynthesis #RNA and protein synthesis mechanisms

paper · pdf · doi:10.1128/aem.00338-23

openalex publication_date 2023/05/31 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

Abstract

with antibacterial activity against human and plant pathogens, including those responsible for widespread soft rot in crops and American foulbrood. Our results provide new insight on the natural chemical diversity of phosphonates and suggest that these compounds could be developed as effective antibiotics for use in medicine or agriculture.

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