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Philip Seeman

  1. Increased dopamine D 2 receptor binding after long-term treatment with antipsychotics in humans: a clinical PET study
    2000/10/06 by S. Silvestri, Simone Silvestri, Mary V. Seeman +11 · 33 citations
    Medicine · Neuroscience · Psychology · #Antipsychotic #Dopamine #Dopamine receptor #Dopamine receptor D2 #Haloperidol #Internal medicine #Medicine #Neurotransmitter Receptor Influence on Behavior #Olanzapine #Pharmacology #Psychiatry #Psychology #Raclopride #Receptor #Risperidone #Schizophrenia (object-oriented programming) #Schizophrenia research and treatment #Sertindole #Tardive dyskinesia #Tryptophan and brain disorders
  2. NMDA receptor antagonists ketamine and PCP have direct effects on the dopamine D2 and serotonin 5-HT2 receptors—implications for models of schizophrenia
    2002/09/01 by Shitij Kapur, S Kapur, Philip Seeman +1 · 7 citations
    Medicine · Neuroscience · #Neurotransmitter Receptor Influence on Behavior #Treatment of Major Depression #Tryptophan and brain disorders
  3. Dopamine D2Highreceptors stimulated by phencyclidines, lysergic acid diethylamide, salvinorin A, and modafinil
    2009/04/23 by Philip Seeman, Hong‐Chang Guan, Hélène Hirbec · 4 citations
    Neuroscience · Biochemistry, Genetics and Molecular Biology · #Neurotransmitter Receptor Influence on Behavior #Receptor Mechanisms and Signaling #Pharmacological Receptor Mechanisms and Effects
  4. Phencyclidine and glutamate agonist LY379268 stimulate dopamine D2Highreceptors: D2 basis for schizophrenia
    2008/08/20 by Philip Seeman, Hong‐Chang Guan · 3 citations
    Neuroscience · Biochemistry, Genetics and Molecular Biology · #Neuroscience and Neuropharmacology Research #Receptor Mechanisms and Signaling #Neurotransmitter Receptor Influence on Behavior
  5. Atypical Antipsychotics: Mechanism of Action
    2004/01/01 by Philip Seeman · 1 citation
    Chemistry · Medicine · #Amisulpride #Antipsychotic #Aripiprazole #Atypical antipsychotic #Chemistry #Chlorpromazine #Clozapine #Dopamine #Dopamine receptor D2 #Electroconvulsive Therapy Studies #Extrapyramidal symptoms #Haloperidol #Internal medicine #Medicine #Olanzapine #Pharmacology #Psychiatry #Quetiapine #Schizophrenia (object-oriented programming) #Schizophrenia research and treatment #Sertindole #Treatment of Major Depression #Ziprasidone
  6. Cloning and characterization of additional members of the G protein-coupled receptor family
    2000/02/01 by Dennis K. Lee, Kevin R. Lynch, Tuan Nguyen +14 · 1 citation
    Biochemistry, Genetics and Molecular Biology · Neuroscience · Nursing · #Biochemical Analysis and Sensing Techniques #Neuropeptides and Animal Physiology #Receptor Mechanisms and Signaling