Gad Getz
- The mutational constraint spectrum quantified from variation in 141,456 humans
2020/05/27 by Konrad J. Karczewski, Laurent C. Francioli, Grace Tiao +97 · 168 citations
Biochemistry, Genetics and Molecular Biology · #CRISPR and Genetic Engineering #Genomics and Phylogenetic Studies #Genomics and Rare Diseases
- The GTEx Consortium atlas of genetic regulatory effects across human tissues
2020/09/10 by François Aguet, Shankara Anand, Kristin Ardlie +97 · 107 citations
Biochemistry, Genetics and Molecular Biology · #RNA Research and Splicing #RNA modifications and cancer #Genomics and Chromatin Dynamics
- The Genotype-Tissue Expression (GTEx) project
2013/05/29 by John Lonsdale, Jeffrey Thomas, Mike Salvatore +124 · 42 citations
- The repertoire of mutational signatures in human cancer
2020/02/05 by PCAWG Mutational Signatures Working Group, Erik N. Bergstrom, Arnoud Boot +76 · 49 citations
Biochemistry, Genetics and Molecular Biology · #Cancer Genomics and Diagnostics #Evolution and Genetic Dynamics #Genomics and Rare Diseases
- A genomic mutational constraint map using variation in 76,156 human genomes
2023/12/06 by Siwei Chen, Laurent C. Francioli, Julia K. Goodrich +254 · 68 citations
Biochemistry, Genetics and Molecular Biology · #Genomic variations and chromosomal abnormalities #Genomics and Chromatin Dynamics #Genomics and Rare Diseases
- Genetic and transcriptional evolution alters cancer cell line drug response
2018/08/01 by Uri Ben-David, Uri Ben‐David, Benjamin Siranosian +34 · 12 citations
Biochemistry, Genetics and Molecular Biology · #Cancer Genomics and Diagnostics #Gene expression and cancer classification #Single-cell and spatial transcriptomics
- Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma
2020/07/01 by Michael A. Gillette, Shankha Satpathy, Song Cao +199 · 11 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #RNA modifications and cancer #Ferroptosis and cancer prognosis #Lung Cancer Treatments and Mutations
- CXCL9:SPP1 macrophage polarity identifies a network of cellular programs that control human cancers
2023/08/03 by Ruben Bill, Pratyaksha Wirapati, Marius Messemaker +30 · 14 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Epigenetics and DNA Methylation #Ferroptosis and cancer prognosis #Immune cells in cancer
- Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
2020/02/05 by Ruibin Xi, Dhawal Jain, Youngsook L. Jung +1341 · 10 citations
Biochemistry, Genetics and Molecular Biology · #Cancer Genomics and Diagnostics #Genomic variations and chromosomal abnormalities #Genomics and Rare Diseases
- Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy
2020/11/01 by Karsten Krug, Eric J. Jaehnig, Shankha Satpathy +104 · 8 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Advanced Proteomics Techniques and Applications #Bioinformatics and Genomic Networks #Ferroptosis and cancer prognosis
- Design Principle of Gene Expression Used by Human Stem Cells; Implication for Pluripotency
2004/09/15 by Michal Golan‐Mashiach, Michal Golan-Mashiach, Jean-Eudes Dazard +31 · 1 citation
Biochemistry, Genetics and Molecular Biology · #CRISPR and Genetic Engineering #FOS: Biological sciences #Other Quantitative Biology (q-bio.OT) #Pluripotent Stem Cells Research #Quantitative Methods (q-bio.QM) #Single-cell and spatial transcriptomics #q-bio.OT #q-bio.QM
- Semi-Supervised Learning -- A Statistical Physics Approach
2006/04/05 by Gad Getz, Noam Shental, Getz, Gad +3 · 1 citation
Computer Science · #Anomaly Detection Techniques and Applications #Computer Vision and Pattern Recognition (cs.CV) #FOS: Computer and information sciences #FOS: Physical sciences #Gaussian Processes and Bayesian Inference #Machine Learning (cs.LG) #Neural Networks and Applications #Statistical Mechanics (cond-mat.stat-mech)
- Computational Pathology: An Emerging Definition
2014/08/29 by David N. Louis, Georg K. Gerber, Jason M. Baron +13 · 1 citation
Computer Science · #AI in cancer detection
- The landscape of primary mismatch repair deficient gliomas in children, adolescents, and young adults: a multi-cohort study
2024/12/16 by Logine Negm, Jiil Chung, Liana Nobre +68 · 1 voice · 1 citation
Medicine · #Ferroptosis and cancer prognosis #Genetic factors in colorectal cancer #Glioma Diagnosis and Treatment