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Stuart H. Orkin

  1. Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression
    2003/07/01 by Carola A. Neumann, Daniela S. Krause, Christopher V. Carman +7 · 3 citations
    Biochemistry, Genetics and Molecular Biology · #Glutathione Transferases and Polymorphisms #Heat shock proteins research #Redox biology and oxidative stress
  2. Polycomb Repressive Complex 2 Is a Barrier to KRAS-Driven Inflammation and Epithelial-Mesenchymal Transition in Non-Small-Cell Lung Cancer
    2016/01/01 by Michela Serresi, Gaetano Gargiulo, Natalie Proost +12 · 1 voice · 3 citations
    Biochemistry, Genetics and Molecular Biology · Medicine · #Cancer Cells and Metastasis #Epigenetics and DNA Methylation #Hippo pathway signaling and YAP/TAZ
  3. Mapping the Mouse Cell Atlas by Microwell-Seq
    2018/02/01 by Xiaoping Han, Renying Wang, Yincong Zhou +26 · 1 voice · 1 citation
    Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Cell Image Analysis Techniques #Immune cells in cancer #Single-cell and spatial transcriptomics
  4. Correction of Sickle Cell Disease in Adult Mice by Interference with Fetal Hemoglobin Silencing
    2011/10/14 by Jian Xu, Cong Peng, Vijay G. Sankaran +8 · 1 citation
    Medicine · #Blood groups and transfusion #Hemoglobinopathies and Related Disorders #Iron Metabolism and Disorders
  5. THE MUTATION AND POLYMORPHISM OF THE HUMAN β-GLOBIN GENE AND ITS SURROUNDING DNA
    1984/12/01 by Stuart H. Orkin, Haig H. Kazazian · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Animal Genetics and Reproduction #RNA and protein synthesis mechanisms #CRISPR and Genetic Engineering
  6. Somatic gene therapy. Current status and future prospects.
    1986/04/01 by D A Williams, David A. Williams, S H Orkin +1 · 1 citation
    Biochemistry, Genetics and Molecular Biology · #Animal Genetics and Reproduction #CRISPR and Genetic Engineering #Virus-based gene therapy research
  7. Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoeitin/MGDF in megakaryocyte development
    1995/06/01 by Ramesh A Shivdasani, Ramesh A. Shivdasani, Margery F Rosenblatt +11 · 1 citation
    Medicine · #Blood properties and coagulation #Myeloproliferative Neoplasms: Diagnosis and Treatment #Platelet Disorders and Treatments