R. Scott Obach

1. Mechanism-Based Inactivation of Human Cytochrome P450 Enzymes and the Prediction of Drug-Drug Interactions
   2006/11/09 by R. Scott Obach, Robert L. Walsky, Karthik Venkatakrishnan · 4 citations
   Pharmacology, Toxicology and Pharmaceutics · Medicine · #Pharmacogenetics and Drug Metabolism #Drug Transport and Resistance Mechanisms #Pharmacological Effects and Toxicity Studies
2. The Utility of in Vitro Cytochrome P450 Inhibition Data in the Prediction of Drug-Drug Interactions
   2005/12/21 by R. Scott Obach, Robert L. Walsky, Karthik Venkatakrishnan +3 · 28 citations
   Pharmacology, Toxicology and Pharmaceutics · Medicine · Computer Science · #Pharmacogenetics and Drug Metabolism #Drug Transport and Resistance Mechanisms #Computational Drug Discovery Methods
3. Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 1352 Drug Compounds
   2018/08/16 by Franco Lombardo, Giuliano Berellini, R. Scott Obach · 3 citations
   Chemistry · Computer Science · Pharmacology, Toxicology and Pharmaceutics · #Analytical Chemistry and Chromatography #Computational Drug Discovery Methods #Pharmacogenetics and Drug Metabolism
4. Evaluation of Various Static and Dynamic Modeling Methods to Predict Clinical CYP3A Induction Using In Vitro CYP3A4 mRNA Induction Data
   2013/08/29 by Heidi J. Einolf, H J Einolf, L Chen +16 · 16 citations
   Pharmacology, Toxicology and Pharmaceutics · Mathematics · Immunology and Microbiology · #Pharmacogenetics and Drug Metabolism #Statistical Methods in Clinical Trials #Biosimilars and Bioanalytical Methods