Marcela Moncada‐Vélez
- Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths
2021/08/10 by Paul Bastard, Adrian Gervais, Tom Le Voyer +97 · 1 voice · 31 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #SARS-CoV-2 and COVID-19 Research #COVID-19 Clinical Research Studies #Diabetes and associated disorders
- Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
2020/09/24 by Qian Zhang, Paul Bastard, Zhiyong Liu +97 · 23 citations
Immunology and Microbiology · Biochemistry, Genetics and Molecular Biology · #Immunodeficiency and Autoimmune Disorders #Blood disorders and treatments #Diabetes and associated disorders
- The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
2022/05/16 by Jérémy Manry, Paul Bastard, Adrian Gervais +97 · 1 voice · 5 citations
Medicine · #COVID-19 Clinical Research Studies #Long-Term Effects of COVID-19 #SARS-CoV-2 and COVID-19 Research
- A common form of dominant human IFNAR1 deficiency impairs IFN-α and -ω but not IFN-β-dependent immunity
2024/12/16 by Fahd Al Qureshah, Jérémie Le Pen, Nicole A. de Weerd +91 · 3 voices · 1 citation
Immunology and Microbiology · #interferon and immune responses #Immune Cell Function and Interaction #Immunodeficiency and Autoimmune Disorders
- Autoantibodies neutralizing type I IFNs in a fatal case of H5N1 avian influenza
2025/11/18 by Qian Zhang, Taylor Conrad, Marcela Moncada‐Vélez +15 · 1 voice · 5 citations
Immunology and Microbiology · Medicine · #interferon and immune responses #Influenza Virus Research Studies #Respiratory viral infections research