Marco Colonna
- TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques
2016/04/18 by Yaming Wang, Tyler K. Ulland, Jason D. Ulrich +14 · 39 citations
Neuroscience · Immunology and Microbiology · #Neuroinflammation and Neurodegeneration Mechanisms #Inflammation biomarkers and pathways #Neurological Disease Mechanisms and Treatments
- Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease
2020/01/01 by Yingyue Zhou, Wilbur M. Song, Prabhakar S. Andhey +23 · 28 citations
Immunology and Microbiology · Medicine · Neuroscience · #Inflammation biomarkers and pathways #Medicinal Plants and Neuroprotection #Neuroinflammation and Neurodegeneration Mechanisms
- Microglia states and nomenclature: A field at its crossroads
2022/11/01 by Rosa C. Paolicelli, Rosa Chiara Paolicelli, Amanda Sierra +118 · 30 citations
Immunology and Microbiology · Medicine · Neuroscience · #Chemokine receptors and signaling #Immune cells in cancer #Neuroinflammation and Neurodegeneration Mechanisms
- Negative feedback control of neuronal activity by microglia
2020/09/30 by Ana Badimon, Hayley J. Strasburger, Pinar Ayata +30 · 18 citations
Biochemistry, Genetics and Molecular Biology · Neuroscience · #Adenosine and Purinergic Signaling #Neuroinflammation and Neurodegeneration Mechanisms #Neuroscience and Neuropharmacology Research
- Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma
2021/06/03 by Andrea Cugurra, Tornike Mamuladze, Justin Rustenhoven +14 · 17 citations
Immunology and Microbiology · Medicine · Neuroscience · #Immune cells in cancer #Neuroinflammation and Neurodegeneration Mechanisms #Traumatic Brain Injury and Neurovascular Disturbances
- TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy
2020/08/01 by Martina Molgora, Ekaterina Esaulova, William Vermi +19 · 14 citations
Immunology and Microbiology · Neuroscience · #Immune cells in cancer #Inflammation biomarkers and pathways #Neuroinflammation and Neurodegeneration Mechanisms
- Microglia Function in the Central Nervous System During Health and Neurodegeneration
2017/04/26 by Marco Colonna, Oleg Butovsky · 7 citations
- Meningeal lymphatics-microglia axis regulates synaptic physiology
2025/03/22 by Kyungdeok Kim, Daviti Abramishvili, Siling Du +7 · 1 voice · 5 citations
Neuroscience · #Neuroinflammation and Neurodegeneration Mechanisms #Cerebrospinal fluid and hydrocephalus #Neurogenesis and neuroplasticity mechanisms
- Rorγt-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens
2025/04/05 by Patrick Fernandes Rodrigues, Shitong Wu, Tihana Tršan +14 · 1 voice · 3 citations
Immunology and Microbiology · #IL-33, ST2, and ILC Pathways #Immune Cell Function and Interaction #T-cell and B-cell Immunology
- Loss of ATG7 in microglia impairs UPR, triggers ferroptosis, and weakens amyloid pathology control
2025/02/13 by Zhangying Cai, Shoutang Wang, Siyan Cao +9 · 1 voice · 1 citation
Medicine · Neuroscience · #Autophagy in Disease and Therapy #Ferroptosis and cancer prognosis #Neuroinflammation and Neurodegeneration Mechanisms