Elizabeth M. Jaffee
- CXCR2 blockade overcomes the NETosis-mediated resistance to MEK inhibition in pancreatic cancer models
2026/03/19 by Brian Herbst, Alex B. Blair, Yiming Li +2 · 1 voice
Immunology and Microbiology · Medicine · #Chemokine receptors and signaling #Neutrophil, Myeloperoxidase and Oxidative Mechanisms #Phagocytosis and Immune Regulation
- The Rising Burden of Early-Onset Cancer: Challenges and Opportunities
2026/06/01 by Andrea Cercek, Daniel J. Zabransky, Gianluca Mauri +3 · 1 voice
Environmental Science · Medicine · #Acute Lymphoblastic Leukemia research #Birth, Development, and Health #Health, Environment, Cognitive Aging
- An integrated single-cell and spatial transcriptomic atlas of thyroid cancer progression identifies prognostic fibroblast subpopulations
2026/01/01 by Matthew A. Loberg, George J. Xu, Sheau‐Chiann Chen +31 · 1 voice
Medicine · Biochemistry, Genetics and Molecular Biology · #Thyroid Cancer Diagnosis and Treatment #Single-cell and spatial transcriptomics #Ferroptosis and cancer prognosis
- Copanlisib in combination with nivolumab formicrosatellite stable colorectal cancer: a phase 1/2 trial
2026/07/23 by Eric S. Christenson, Jeremiah A. Wala, Rose Parkinson +24 · 1 voice
Biochemistry, Genetics and Molecular Biology · Medicine · #Cancer Immunotherapy and Biomarkers #Colorectal Cancer Treatments and Studies #PI3K/AKT/mTOR signaling in cancer
- First-in-human testing of a mutant KRAS vaccine for pancreatic cancer interception in high-risk cohorts
2026/07/16 by Saurav D. Haldar, Amanda L. Huff, Hejia Wang +25 · 1 voice
Immunology and Microbiology · Medicine · #Immunotherapy and Immune Responses #Pancreatic and Hepatic Oncology Research #Pancreatitis Pathology and Treatment
- A Randomized Phase II Study: CRS207/GVAX plus Anti–PD-1 and Anti-CTLA4 Recruits Mesothelin- and mKRAS-Specific T Cells into PDAC
2026/01/12 by Katherine M. Bever, Amanda Huff, Ludmila Danilova +16 · 1 voice
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Immunotherapy and Immune Responses #Pancreatic and Hepatic Oncology Research #vaccines and immunoinformatics approaches