Christine Orengo
- InterPro in 2022
2022/11/09 by Typhaine Paysan‐Lafosse, Typhaine Paysan-Lafosse, Matthias Blum +36 · 112 citations
Biochemistry, Genetics and Molecular Biology · Materials Science · #Enzyme Structure and Function #Machine Learning in Bioinformatics #Protein Structure and Dynamics
- The InterPro protein families and domains database: 20 years on
2020/10/23 by Matthias Blum, Hsin-Yu Chang, Sara Chuguransky +30 · 80 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Materials Science · #Advanced Proteomics Techniques and Applications #Enzyme Structure and Function #Genomics and Phylogenetic Studies
- Exploring structural diversity across the protein universe with The Encyclopedia of Domains
2024/10/31 by Andy M. Lau, Nicola Bordin, Shaun M. Kandathil +5 · 1 voice · 15 citations
Biochemistry, Genetics and Molecular Biology · #Bioinformatics and Genomic Networks #Genomics and Phylogenetic Studies #Protein Structure and Dynamics
- Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination
2013/06/24 by Florence R. Fricker, Ana Antunes-Martins, Ana Antunes‐Martins +14 · 28 citations
Medicine · Neuroscience · #Amphiregulin #Axon #Biology #Cell biology #Central nervous system #Growth factor #Hereditary Neurological Disorders #Internal medicine #Medicine #Myelin #Nerve injury #Nerve injury and regeneration #Neuregulin #Neuregulin 1 #Neurogenesis and neuroplasticity mechanisms #Neuroscience #Receptor #Remyelination #Schwann cell #Signal transduction #Wallerian degeneration
- PROTEIN FAMILIES AND THEIR EVOLUTION—A STRUCTURAL PERSPECTIVE
2005/06/01 by Christine Orengo, Janet M. Thornton · 4 citations
Biochemistry, Genetics and Molecular Biology · #Genomics and Phylogenetic Studies #RNA and protein synthesis mechanisms #Machine Learning in Bioinformatics
- 3D-Beacons: decreasing the gap between protein sequences and structures through a federated network of protein structure data resources
2022/01/01 by Mihály Váradi, Sreenath Nair, Ian Sillitoe +29 · 1 voice · 2 citations
Biochemistry, Genetics and Molecular Biology · Engineering · #Biofuel production and bioconversion #Bioinformatics and Genomic Networks #Microbial Metabolic Engineering and Bioproduction
- SARS-CoV-2 spike protein predicted to form complexes with host receptor protein orthologues from a broad range of mammals
2020/10/05 by Su Datt Lam, Nicola Bordin, Vaishali Waman +14 · 3 citations
Medicine · Agricultural and Biological Sciences · #SARS-CoV-2 and COVID-19 Research #Animal Virus Infections Studies #COVID-19 Clinical Research Studies
- Review of protein structure-based analyses that illuminate plant stress mechanisms
2025/01/01 by Fatima Shahid, Neeladri Sen, Hawa Najibah Rasni +4 · 1 voice · 1 citation
Agricultural and Biological Sciences · #Plant Stress Responses and Tolerance #Plant nutrient uptake and metabolism #Plant responses to water stress
- Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use
2016/03/16 by Harshnira Hitesh Patani, Tom D. Bunney, Nethaji Thiyagarajan +14 · 1 citation
Biochemistry, Genetics and Molecular Biology · #Fibroblast Growth Factor Research #Kruppel-like factors research #Epigenetics and DNA Methylation
- A CATH domain functional family based approach to identify putative cancer driver genes and driver mutations
2019/01/22 by Paul Ashford, Camilla Pang, Aurelio A. Moya‐García +2 · 1 citation
Biochemistry, Genetics and Molecular Biology · #Bioinformatics and Genomic Networks #Genomics and Phylogenetic Studies #CRISPR and Genetic Engineering