Stuart G. Tangye

1. Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths
   2021/08/10 by Paul Bastard, Adrian Gervais, Tom Le Voyer +97 · 1 voice · 56 citations
   Medicine · Biochemistry, Genetics and Molecular Biology · #SARS-CoV-2 and COVID-19 Research #COVID-19 Clinical Research Studies #Diabetes and associated disorders
2. Autoantibodies against type I IFNs in patients with life-threatening COVID-19
   2020/09/24 by Paul Bastard, Lindsey B. Rosen, Qian Zhang +97 · 1 voice · 31 citations
   Biochemistry, Genetics and Molecular Biology · Medicine · #COVID-19 Clinical Research Studies #Diabetes and associated disorders #SARS-CoV-2 and COVID-19 Research
3. Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee
   2020/01/01 by Stuart G. Tangye, Waleed Al–Herz, Aziz Bousfiha +14 · 16 citations
   Immunology and Microbiology · Medicine · #Cystic Fibrosis Research Advances #Immunodeficiency and Autoimmune Disorders #Tumors and Oncological Cases
4. Human Inborn Errors of Immunity: 2022 Update on the Classification from the International Union of Immunological Societies Expert Committee
   2022/06/24 by Stuart G. Tangye, Waleed Al–Herz, Aziz Bousfiha +15 · 18 citations
   Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Blood disorders and treatments #Immunodeficiency and Autoimmune Disorders #Parvovirus B19 Infection Studies
5. The origins, function, and regulation of T follicular helper cells
   2012/07/02 by Cindy S. Ma, S. Cindy, Elissa K. Deenick +2 · 27 citations
   Immunology and Microbiology · #T-cell and B-cell Immunology #Immune Cell Function and Interaction #Immunotherapy and Immune Responses
6. Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus
   2009/12/28 by Nicholas Simpson, Paul A. Gatenby, Anastasia Wilson +12 · 27 citations
   Immunology and Microbiology · Medicine · Biochemistry, Genetics and Molecular Biology · #T-cell and B-cell Immunology #Systemic Lupus Erythematosus Research #Diabetes and associated disorders
7. Human type I IFN deficiency does not impair B cell response to SARS-CoV-2 mRNA vaccination
   2022/10/06 by Aurélien Sokal, Paul Bastard, Pascal Chappert +64 · 25 citations
   Medicine · Immunology and Microbiology · Biochemistry, Genetics and Molecular Biology · #SARS-CoV-2 and COVID-19 Research #Immune Cell Function and Interaction #Diabetes and associated disorders
8. The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
   2022/05/16 by Jérémy Manry, Paul Bastard, Adrian Gervais +97 · 1 voice · 5 citations
   Medicine · #COVID-19 Clinical Research Studies #Long-Term Effects of COVID-19 #SARS-CoV-2 and COVID-19 Research
9. Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification
   2020/01/01 by Aziz Bousfiha, Leïla Jeddane, Capucine Pïcard +16 · 7 citations
   Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · Medicine · #Blood disorders and treatments #Immunodeficiency and Autoimmune Disorders #Tumors and Oncological Cases
10. A common form of dominant human IFNAR1 deficiency impairs IFN-α and -ω but not IFN-β-dependent immunity
    2024/12/16 by Fahd Al Qureshah, Jérémie Le Pen, Nicole A. de Weerd +91 · 3 voices · 1 citation
    Immunology and Microbiology · #interferon and immune responses #Immune Cell Function and Interaction #Immunodeficiency and Autoimmune Disorders
11. Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome
    2015/08/24 by Alexandra Y. Kreins, Michael J. Ciancanelli, Satoshi Okada +51 · 1 voice · 1 citation
    Immunology and Microbiology · #Immunodeficiency and Autoimmune Disorders #Immune Cell Function and Interaction #T-cell and B-cell Immunology