Amelie Stein
- A structural biology community assessment of AlphaFold2 applications
2022/11/01 by Mehmet Akdel, Douglas E. V. Pires, Eduard Porta‐Pardo +31 · 1 voice · 45 citations
Biochemistry, Genetics and Molecular Biology · Computer Science · Materials Science · #Computational Drug Discovery Methods #Enzyme Structure and Function #Protein Structure and Dynamics
- Discovering functionally important sites in proteins
2023/07/13 by Matteo Cagiada, Sandro Bottaro, Søren Lindemose +4 · 1 voice · 10 citations
Biochemistry, Genetics and Molecular Biology · #Biochemical and Molecular Research #RNA modifications and cancer #Genomics and Rare Diseases
- Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations
2017/04/19 by Sofie V. Nielsen, Amelie Stein, Alexander B. Dinitzen +7 · 1 voice · 5 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Cancer Genomics and Diagnostics #Genetic factors in colorectal cancer #Genomics and Rare Diseases
- Rapid protein stability prediction using deep learning representations
2023/05/15 by Lasse M. Blaabjerg, Maher M. Kassem, Lydia L. Good +6 · 1 voice · 11 citations
Biochemistry, Genetics and Molecular Biology · Materials Science · #Enzyme Structure and Function #Machine Learning in Bioinformatics #Protein Structure and Dynamics
- A mutational atlas for Parkin proteostasis
2024/02/20 by Lene Clausen, Vasileios Voutsinos, Matteo Cagiada +10 · 1 voice · 7 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Autophagy in Disease and Therapy #Parkinson's Disease Mechanisms and Treatments #Ubiquitin and proteasome pathways
- Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants
2024/05/13 by Martin Grønbæk-Thygesen, Vasileios Voutsinos, Kristoffer E. Johansson +10 · 1 voice · 4 citations
Biochemistry, Genetics and Molecular Biology · Materials Science · #Biochemical and Molecular Research #Enzyme Structure and Function #Ubiquitin and proteasome pathways
- SSEmb: A joint embedding of protein sequence and structure enables robust variant effect predictions
2024/11/07 by Lasse M. Blaabjerg, Nicolas Jonsson, Wouter Boomsma +2 · 1 voice · 5 citations
Biochemistry, Genetics and Molecular Biology · #Genomics and Phylogenetic Studies #Genomics and Rare Diseases #Machine Learning in Bioinformatics
- Disease-linked mutations cause exposure of a protein quality control degron
2022/06/13 by Caroline Kampmeyer, Sven Larsen-Ledet, Morten Rose Wagnkilde +14 · 3 citations
Biochemistry, Genetics and Molecular Biology · #Endoplasmic Reticulum Stress and Disease #Heat shock proteins research #Ubiquitin and proteasome pathways
- A near-complete map of human cytosolic degrons and their relevance for disease
2026/02/06 by Vasileios Voutsinos, Kristoffer E. Johansson, Fia B. Larsen +8 · 1 voice · 5 citations
Biochemistry, Genetics and Molecular Biology · #Ubiquitin and proteasome pathways #Protein Degradation and Inhibitors #Cell death mechanisms and regulation