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Russell Smith

  1. Covalent pan-TEAD inhibitors block YAP activity and demonstrate brain penetrance in a Hippo-dependent cancer model
    2026/06/27 by Thijs J. Hagenbeek, Jason Zbieg, Russell Smith +51 · 1 voice
    Biochemistry, Genetics and Molecular Biology · Neuroscience · #Axon Guidance and Neuronal Signaling #Cancer #Hedgehog signaling pathway #Hippo pathway signaling and YAP/TAZ #Hippo signaling pathway #In vitro #In vivo #Signal transduction #Small molecule #Transcription (linguistics) #Transcription factor #Wnt/β-catenin signaling in development and cancer