Bruce M. Psaty
- The cardiovascular health study: Design and rationale
1991/02/01 by Linda P. Fried, Nemat O. Borhani, Paul Enright +16 · 21 citations
Medicine · #Cardiovascular Health and Risk Factors #Health Promotion and Cardiovascular Prevention #Nutritional Studies and Diet
- Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
2021/09/01 by Urmo Võsa, Annique Claringbould, Harm-Jan Westra +124 · 40 citations
Biochemistry, Genetics and Molecular Biology · #Bioinformatics and Genomic Networks #Genetic Associations and Epidemiology #Single-cell and spatial transcriptomics
- KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference
2016/11/28 by Günter Schumann, Chunyu Liu, Paul F. O’Reilly +97 · 1 voice · 7 citations
Biochemistry, Genetics and Molecular Biology · #Fibroblast Growth Factor Research #Genetic Syndromes and Imprinting #Kruppel-like factors research
- The Medical Cost of Undiagnosed Sleep Apnea
1999/09/01 by Vishesh K. Kapur, David K. Blough, Robert E. Sandblom +4 · 5 citations
Medicine · #Anesthesia #Apnea #Apnea–hypopnea index #Body mass index #Breathing #Central sleep apnea #Emergency medicine #Hypopnea #Internal medicine #Medicine #Obstructive Sleep Apnea Research #Obstructive sleep apnea #Pediatrics #Physical therapy #Polysomnography #Sleep apnea
- Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects
2018/01/01 by Carolina Medina‐Gómez, Carolina Medina-Gomez, John P. Kemp +111 · 28 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Psychology · #Association (psychology) #Biology #Developmental psychology #Epigenetics and DNA Methylation #Gene #Genetic Associations and Epidemiology #Genetics #Genome-wide association study #Genotype #Internal medicine #Life course approach #Medicine #Meta-analysis #Nutrition, Genetics, and Disease #Psychology #Single-nucleotide polymorphism
- Health Outcomes Associated With Various Antihypertensive Therapies Used as First-Line Agents
2003/05/20 by Bruce M. Psaty, Thomas Lumley, Curt D. Furberg +4 · 3 citations
Medicine · #Blood Pressure and Hypertension Studies #Renin-Angiotensin System Studies #Heart Failure Treatment and Management #Medicine #Relative risk #Placebo #Randomized controlled trial #Internal medicine #Meta-analysis #Heart failure #Stroke (engine) #Clinical trial #Confidence interval #Number needed to harm #Disease #MEDLINE #Intensive care medicine #Number needed to treat #Alternative medicine #Pathology
- Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data
2022/03/01 by Pierrick Wainschtein, Deepti Jain, Zhili Zheng +490 · 3 citations
Biochemistry, Genetics and Molecular Biology · #Genetic Associations and Epidemiology #Genetic Mapping and Diversity in Plants and Animals #Genetic and phenotypic traits in livestock
- Lower Risk of Cardiovascular Events in Postmenopausal Women Taking Oral Estradiol Compared With Oral Conjugated Equine Estrogens
2013/10/01 by Nicholas L. Smith, Marc Blondon, Kerri L. Wiggins +11 · 4 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Menopause: Health Impacts and Treatments #Estrogen and related hormone effects #Hormonal and reproductive studies
- Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders
2018/11/01 by Symen Ligthart, Ahmad Vaez, Urmo Võsa +341 · 26 citations
Biochemistry, Genetics and Molecular Biology · Health Professions · Immunology and Microbiology · #1000 Genomes Project #Adolescent and Pediatric Healthcare #Bioinformatics #Biology #Biomarker #C-reactive protein #Gene #Genetic Associations and Epidemiology #Genetic association #Genetic variants #Genetics #Genome-wide association study #Genotype #IL-33, ST2, and ILC Pathways #Immunology #Inflammation #International HapMap Project #Mendelian randomization #Single-nucleotide polymorphism
- Genetic Variants Associated with Circulating Parathyroid Hormone
2016/12/07 by Cassianne Robinson-Cohen, Pamela L. Lutsey, Marcus E. Kleber +46 · 1 citation
- Whole-Genome Sequencing Association Analyses of Stroke and Its Subtypes in Ancestrally Diverse Populations From Trans-Omics for Precision Medicine Project
2021/11/03 by Yao Hu, Jeffrey Haessler, Regina Manansala +36 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Genetic Associations and Epidemiology #Cerebrovascular and genetic disorders #Genomics and Rare Diseases
- Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale
2020/08/24 by Xihao Li, Zilin Li, Hufeng Zhou +450 · 2 citations
Biochemistry, Genetics and Molecular Biology · #Genetic Associations and Epidemiology #Genomic variations and chromosomal abnormalities #Genomics and Rare Diseases
- Genetic Variants Associated with Circulating Fibroblast Growth Factor 23
2018/09/14 by Cassianne Robinson-Cohen, Cassianne Robinson‐Cohen, Traci M. Bartz +32 · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Bone health and treatments #Fibroblast Growth Factor Research #Parathyroid Disorders and Treatments
- A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies
2022/10/27 by Zilin Li, Xihao Li, Hufeng Zhou +531 · 2 citations
Biochemistry, Genetics and Molecular Biology · #Bioinformatics and Genomic Networks #Genetic Associations and Epidemiology #Genomics and Rare Diseases
- Genetic insights into biological mechanisms governing human ovarian ageing
2021/08/04 by Katherine S. Ruth, Felix R. Day, Jazib Hussain +282 · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Genetics, Aging, and Longevity in Model Organisms #Nutrition, Genetics, and Disease #Reproductive Biology and Fertility
- Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies
2022/12/23 by Xihao Li, Corbin Quick, Hufeng Zhou +448 · 1 citation
Biochemistry, Genetics and Molecular Biology · #Bioinformatics and Genomic Networks #Genetic Associations and Epidemiology #Genomics and Rare Diseases