J. Wade Harper
- Cullin-RING Ubiquitin Ligase Regulatory Circuits: A Quarter Century Beyond the F-Box Hypothesis
2021/04/07 by J. Wade Harper, Brenda A. Schulman · 11 citations
Biochemistry, Genetics and Molecular Biology · #Ubiquitin and proteasome pathways #Protein Degradation and Inhibitors #Histone Deacetylase Inhibitors Research
- p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene.
1995/03/15 by Satomi Matsuoka, S Matsuoka, Michael C. Edwards +12 · 4 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Cancer-related Molecular Pathways #Epigenetics and DNA Methylation #Hedgehog Signaling Pathway Studies
- Biallelic Mutations in DNAJC12 Cause Hyperphenylalaninemia, Dystonia, and Intellectual Disability
2017/01/26 by Yair Anikster, Tobias B. Haack, Thierry Vilboux +46 · 25 citations
Biochemistry, Genetics and Molecular Biology · #Metabolism and Genetic Disorders #RNA modifications and cancer #Mitochondrial Function and Pathology
- Cathepsin-dependent amyloid formation drives mechanical rupture of lysosomal membranes
2026/01/19 by D. Li, Wenxin Zhang, Michaela Medina +20 · 1 voice · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · #Lysosomal Storage Disorders Research #Alzheimer's disease research and treatments #Cellular transport and secretion