Jonathan S. Weissman
- Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
2009/08/03 by Julie Hollien, Jonathan H. Lin, Han Li +3 · 34 citations
Biochemistry, Genetics and Molecular Biology · #Endoplasmic Reticulum Stress and Disease #RNA regulation and disease #CRISPR and Genetic Engineering
- A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging
2014/10/01 by Marvin E. Tanenbaum, Marvin E. Tanenbaum, Luke A. Gilbert +7 · 20 citations
Biochemistry, Genetics and Molecular Biology · #CRISPR and Genetic Engineering #Advanced biosensing and bioanalysis techniques #RNA and protein synthesis mechanisms
- A Ribosome-Bound Quality Control Complex Triggers Degradation of Nascent Peptides and Signals Translation Stress
2012/11/01 by Onn Brandman, Jacob Stewart-Ornstein, Daisy Wong +19 · 11 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #RNA and protein synthesis mechanisms #RNA modifications and cancer #Toxin Mechanisms and Immunotoxins
- Lineage tracing reveals the phylodynamics, plasticity, and paths of tumor evolution
2022/05/01 by Dian Yang, Matthew G. Jones, Santiago Naranjo +20 · 1 voice · 14 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Cancer Cells and Metastasis #Cancer Genomics and Diagnostics #Single-cell and spatial transcriptomics
- Oxidative protein folding in eukaryotes
2004/02/02 by Benjamin P. Tu, Jonathan S. Weissman · 27 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Endoplasmic Reticulum Stress and Disease #Autophagy in Disease and Therapy #Heme Oxygenase-1 and Carbon Monoxide
- Deciphering cell states and genealogies of human haematopoiesis
2024/01/22 by Chen Weng, Fulong Yu, Dian Yang +24 · 1 voice · 7 citations
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Immune Cell Function and Interaction #Single-cell and spatial transcriptomics #T-cell and B-cell Immunology
- High-quality peptide evidence for annotating non-canonical open reading frames as human proteins
2024/09/09 by Eric W. Deutsch, Leron W. Kok, Jonathan M. Mudge +40 · 3 voices · 3 citations
Biochemistry, Genetics and Molecular Biology · #Genomics and Phylogenetic Studies #Machine Learning in Bioinformatics #RNA and protein synthesis mechanisms
- A platform for multimodal in vivo pooled genetic screens reveals regulators of liver function
2024/11/21 by Reuben A. Saunders, William E. Allen, Xingjie Pan +8 · 1 voice · 3 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Single-cell and spatial transcriptomics #RNA Research and Splicing #Adipose Tissue and Metabolism
- Large-scale CRISPR screening in primary human 3D gastric organoids enables comprehensive dissection of gene-drug interactions
2025/08/14 by Yuan‐Hung Lo, Hudson T. Horn, Mo-Fan Huang +12 · 1 voice · 3 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #CRISPR and Genetic Engineering #Cancer Cells and Metastasis #Cancer Genomics and Diagnostics
- Transcriptome-wide analysis of differential expression in perturbation atlases
2025/04/21 by Ajay Nadig, Joseph M. Replogle, Angela N. Pogson +5 · 5 citations