Diabetic retinopathy, metabolic memory and epigenetic modifications

2017/07/19 by Renu A. Kowluru · 84 citations
Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Advanced Glycation End Products research #Bioinformatics #Biology #Cell biology #DNA repair #Diabetes mellitus #Diabetic retinopathy #Endocrinology #Epigenetics #Gene #Genetics #Histone #Internal medicine #Medicine #Mitochondrial DNA #Mitochondrion #Neuroinflammation and Neurodegeneration Mechanisms #Oxidative stress #Retinal Diseases and Treatments #Retinopathy

paper · pdf · doi:10.1016/j.visres.2017.02.011

published in Vision Research 139, 30-38 (Elsevier BV)

openalex publication_date 2017/07/19 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/06

Citations

• Metabolic memory and diabetic retinopathy: Role of inflammatory mediators in retinal pericytes
• Oxidative Stress and Diabetic Complications
• Nitric Oxide and Peroxynitrite in Health and Disease

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• Potential Interplay between Hyperosmolarity and Inflammation on Retinal Pigmented Epithelium in Pathogenesis of Diabetic Retinopathy. [europepmc]
• Remodeling of Retinal Architecture in Diabetic Retinopathy: Disruption of Ocular Physiology and Visual Functions by Inflammatory Gene Products and Pyroptosis. [europepmc]
• Serum microRNA-221 as a biomarker for diabetic retinopathy in patients associated with type 2 diabetes. [europepmc]
• Perturbed Biochemical Pathways and Associated Oxidative Stress Lead to Vascular Dysfunctions in Diabetic Retinopathy. [europepmc]
• Mitochondrial Dysfunction in the Aging Retina. [europepmc]
• Astragalus polysaccharides suppresses high glucose-induced metabolic memory in retinal pigment epithelial cells through inhibiting mitochondrial dysfunction-induced apoptosis by regulating miR-195. [europepmc]
• Astragaloside IV protects against diabetic nephropathy via activating eNOS in streptozotocin diabetes-induced rats. [europepmc]
• Oxidative Stress and Microvascular Alterations in Diabetic Retinopathy: Future Therapies. [europepmc]
• Diabetic Retinopathy-An Underdiagnosed and Undertreated Inflammatory, Neuro-Vascular Complication of Diabetes. [europepmc]
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• Do Genomic Factors Play a Role in Diabetic Retinopathy? [europepmc]
• Elucidating the mechanism of action of alpha-1-antitrypsin using retinal pigment epithelium cells exposed to high glucose. Potential use in diabetic retinopathy. [europepmc]
• Mechanisms behind Retinal Ganglion Cell Loss in Diabetes and Therapeutic Approach. [europepmc]
• Epigenetics and Mitochondrial Stability in the Metabolic Memory Phenomenon Associated with Continued Progression of Diabetic Retinopathy. [europepmc]
• Mitochondrial Ceramide Effects on the Retinal Pigment Epithelium in Diabetes. [europepmc]
• Sirtuin (Sirt) 3 Overexpression Prevents Retinopathy in Streptozotocin-Induced Diabetic Rats. [europepmc]
• Update on the Effects of Antioxidants on Diabetic Retinopathy: In Vitro Experiments, Animal Studies and Clinical Trials. [europepmc]
• Importance of the Use of Oxidative Stress Biomarkers and Inflammatory Profile in Aqueous and Vitreous Humor in Diabetic Retinopathy. [europepmc]
• Diabetic Retinopathy: The Role of Mitochondria in the Neural Retina and Microvascular Disease. [europepmc]
• Current understanding of the molecular and cellular pathology of diabetic retinopathy. [europepmc]
• Recent Advancements in the Medical Treatment of Diabetic Retinal Disease. [europepmc]
• Mitochondrial Dynamics in the Metabolic Memory of Diabetic Retinopathy. [europepmc]