AKR1C3 as a potential target for the inhibitory effect of dietary flavonoids

2008/10/20 by Lucie Škarydová, Lucie Živná, Guangming Xiong +3
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Aldose Reductase and Taurine #Free Radicals and Antioxidants #Biochemical effects in animals

paper · doi:10.1016/j.cbi.2008.10.015

Citations

• An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3α-HSD, type 5 17β-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone independent malignancies