Fabrication of a New Magnetic Nanocatalyst and its Application for the Effectual Construction of Pyrimido[4,5-b]Quinolines

2024/11/17 by Zare, Abdolkarim, Barzegar, Marziyeh, Moosavi-Zare, Ahmad Reza
#3-dimethyluracil #5-b]quinoline #6-Amino-1 #Magnetic nanocatalyst #Pyrimido[4 #[Fe3O4@SiO2@RNMe2-SO3H][CF3CO2]

paper · doi:10.57647/j.ijc.2024.1404.43

Abstract

A new magnetic nanocatalyst, namely [Fe3O4@SiO2@RNMe2-SO3H][CF3CO2] (FSRNSC), was fabricated, and characterized using FT-IR, EDS (energy-dispersive X-ray spectroscopy), elemental mapping, FE-SEM (field-emission scanning electron microscopy), XRD (X-ray diffraction), VSM (vibrating-sample magnetometry), TG (thermogravimetric) and DTG (differential thermogravimetric) analyses. It was utilized as a highly effectual and magnetically recoverable catalyst for the construction of pyrimido[4,5-b]quinolines (12 examples) in high yields (15-50 min) and short times (88-96%). The synthesis was performed through the one-pot, three-component reaction of aryl aldehydes, dimedone, and 6-amino-1,3-dimethyluracil in the absence of solvent.

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