Linezolid lock prophylaxis of central venous catheter infection

2024/05/14 by Fennell, J. P., O'Donohoe, M., Cormican, M. +1
#bacteremia #biofilm #blood-stream infection #daptomycin #model #prevention #trial #vancomycin

paper · doi:10.13025/13629

Abstract

Central venous catheter (CVC)-related infections are a major problem for patients requiring long-term venous access and may result in frequent hospital admissions and difficulties in maintaining central venous access. CVC-related blood stream infections are associated with increased duration of inpatient stay and cost approximately (sic) 13 585 per patient [Blot, S. I., Depuydt, P., Annemans, L., Benoit, D., Hoste, E., De Waele, J. J., Decruyenaere, J., Vogelaers, D., Colardyn, F. & Vandewoude, K. H. (2005). Clin Infect Dis 41, 1591-1598]. Antimicrobial lock therapy may prevent CVC-related blood stream infection, preserve central venous access and reduce hospital admissions. In this paper, the impact of linezolid lock prophylaxis in a patient with short bowel syndrome is described.

Related

• Taurolidine–citrate lock solution for the prevention of central line‐associated bloodstream infection in paediatric haematology–oncology and gastrointestinal failure patients with high baseline central‐line associated bloodstream infection rates
• The impact of a bundle for the prevention of central venous catheter-associated bloodstream infections in an pediatric surgery intensive care unit
• Comparative In Vitro Efficacies and Antimicrobial Durabilities of Novel Antimicrobial Central Venous Catheters
• Impact of a modified Broviac maintenance care bundle on bloodstream infections in paediatric cancer patients
• A Central Line Care Maintenance Bundle for the Prevention of Central Line–Associated Bloodstream Infection in Non–Intensive Care Unit Settings