Functional and inflammatory alterations in the lung following exposure of rats to nitrogen mustard

2010/09/30 by Vasanthi R. Sunil, Kinal J. Patel, Jianliang Shen +4 · 57 citations
Agricultural and Biological Sciences · Chemistry · Environmental Science · Medicine · #Air Quality and Health Impacts #Biology #Chemistry #Immunology #Inflammation #Internal medicine #Lung #Medicine #Nitrogen mustard #Pesticide Exposure and Toxicity #Toxic Organic Pollutants Impact #Toxicology

paper · open access · doi:10.1016/j.taap.2010.09.016

published in Toxicology and Applied Pharmacology 250(1), 10-18 (Elsevier BV)

openalex publication_date 2010/09/30 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01

Citations

• Reduced sulfur mustard-induced skin toxicity in cyclooxygenase-2 knockout and celecoxib-treated mice

Cited by

• Sulfur mustard-induced pulmonary injury: therapeutic approaches to mitigating toxicity. [europepmc]
• Role of TNFR1 in lung injury and altered lung function induced by the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide. [europepmc]
• Role of reactive nitrogen species generated via inducible nitric oxide synthase in vesicant-induced lung injury, inflammation and altered lung functioning. [europepmc]
• Attenuation of acute nitrogen mustard-induced lung injury, inflammation and fibrogenesis by a nitric oxide synthase inhibitor. [europepmc]
• Genotoxic stress accelerates age-associated degenerative changes in intervertebral discs. [europepmc]
• Cross-linking of thioredoxin reductase by the sulfur mustard analogue mechlorethamine (methylbis(2-chloroethyl)amine) in human lung epithelial cells and rat lung: selective inhibition of disulfide reduction but not redox cycling. [europepmc]
• Pentoxifylline attenuates nitrogen mustard-induced acute lung injury, oxidative stress and inflammation. [europepmc]
• Characterization of Distinct Macrophage Subpopulations during Nitrogen Mustard-Induced Lung Injury and Fibrosis. [europepmc]
• Thioredoxin Cross-Linking by Nitrogen Mustard in Lung Epithelial Cells: Formation of Multimeric Thioredoxin/Thioredoxin Reductase Complexes and Inhibition of Disulfide Reduction. [europepmc]
• Inflammatory mechanisms of pulmonary injury induced by mustards. [europepmc]
• Mustard vesicant-induced lung injury: Advances in therapy. [europepmc]
• Macrophages and inflammatory mediators in pulmonary injury induced by mustard vesicants. [europepmc]
• Protective Role of Surfactant Protein-D Against Lung Injury and Oxidative Stress Induced by Nitrogen Mustard. [europepmc]
• Regulation of Macrophage Foam Cell Formation During Nitrogen Mustard (NM)-Induced Pulmonary Fibrosis by Lung Lipids. [europepmc]
• Lung injury, oxidative stress and fibrosis in mice following exposure to nitrogen mustard. [europepmc]
• Disease-modifying treatment of chemical threat agent-induced acute lung injury. [europepmc]
• Transcriptional profiling of lung macrophages during pulmonary injury induced by nitrogen mustard. [europepmc]
• Assessment of mustard vesicant lung injury and anti-TNF-α efficacy in rodents using live-animal imaging. [europepmc]
• Macrophage activation in the lung during the progression of nitrogen mustard induced injury is associated with histone modifications and altered miRNA expression. [europepmc]
• Sex-Related Differences in Murine Models of Chemically Induced Pulmonary Fibrosis. [europepmc]
• Mast Cells Promote Nitrogen Mustard-Mediated Toxicity in the Lung Associated With Proinflammatory Cytokine and Bioactive Lipid Mediator Production. [europepmc]
• MG53 attenuates nitrogen mustard-induced acute lung injury. [europepmc]
• A review of chemical warfare agents linked to respiratory and neurological effects experienced in Gulf War Illness. [europepmc]
• Melatonin as Modulator for Sulfur and Nitrogen Mustard-Induced Inflammation, Oxidative Stress and DNA Damage: Molecular Therapeutics. [europepmc]
• Suppression of Lung Oxidative Stress, Inflammation, and Fibrosis following Nitrogen Mustard Exposure by the Selective Farnesoid X Receptor Agonist Obeticholic Acid. [europepmc]