Goniothalamin prevents the development of chemically induced and spontaneous colitis in rodents and induces apoptosis in the HT-29 human colon tumor cell line

2016/03/22 by Débora Barbosa Vendramini-Costa, Débora B. Vendramini‐Costa, Antonio Montero Alcaide +12 · 5 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Apoptosis #Biochemistry #Cancer #Cancer research #Caspase #Chemistry #Colitis #Colorectal cancer #Downregulation and upregulation #Ginger and Zingiberaceae research #Immunology #Inflammation #Internal medicine #Medicine #Natural product bioactivities and synthesis #Pharmacology #Programmed cell death #Traditional and Medicinal Uses of Annonaceae

paper · doi:10.1016/j.taap.2016.03.009

openalex publication_date 2016/03/22 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/06

Citations

• Anti-inflammatory and antinociceptive effects of racemic goniothalamin, a styryl lactone

Cited by

• Mechanism of apoptosis induction associated with ERK1/2 upregulation via goniothalamin in melanoma cells. [europepmc]
• Preferential Mitochondrial Localization of a Goniothalamin Fluorescent Derivative. [europepmc]
• Hydroxypropyl- β -Cyclodextrin Complexes of Styryllactones Enhance the Anti-Tumor Effect in SW1116 Cell Line. [europepmc]
• Effect of TrkB-PLC/IP3 pathway on intestinal inflammatory factors and enterocyte apoptosis in mice with colitis. [europepmc]
• In vitro models and ex vivo systems used in inflammatory bowel disease. [europepmc]