One-pot synthesis of polysubstituted quinazolin-4(3H)-ones via sequential oxidative Ugi/Staudinger/aza-Wittig reactions starting from tertiary amines

2021/08/04 by Mei Sun, Yan-Ling Yu, Long Zhao +2 · 6 citations
Chemistry · #Azide #Biochemistry #Catalysis #Chemistry #Combinatorial chemistry #Multicomponent Synthesis of Heterocycles #Organic chemistry #Oxidative phosphorylation #Quinazolinone synthesis and applications #Staudinger reaction #Synthesis and biological activity #Triphenylphosphine #Wittig reaction

paper · doi:10.1016/j.tet.2021.132368

published in Tetrahedron 96, 132368 (Elsevier BV)

openalex publication_date 2021/08/04 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Citations

• Über neue organische Phosphorverbindungen III. Phosphinmethylenderivate und Phosphinimine
• Metal–Ligand Cooperative Approach To Achieve Dehydrogenative Functionalization of Alcohols to Quinolines and Quinazolin-4(3H)-ones under Mild Aerobic Conditions

Cited by

• New efficient synthesis of polysubstituted 3,4-dihydroquinazolines and 4 H -3,1-benzothiazines through a Passerini/Staudinger/aza-Wittig/addition/nucleophilic substitution sequence. [europepmc]
• One-pot synthesis of quinazolinone heterocyclic compounds using functionalized SBA-15 with natural material ellagic acid as a novel nanocatalyst. [europepmc]