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INR-LDDMM: Fluid-based Medical Image Registration Integrating Implicit Neural Representation and Large Deformation Diffeomorphic Metric Mapping

2023/08/18 by Chulong Zhang, Zhang, Chulong, Xiaokun Liang +1
Computer Science · Engineering · Neuroscience · #Brain Tumor Detection and Classification #FOS: Electrical engineering #Image and Video Processing (eess.IV) #Medical Image Segmentation Techniques #Medical Imaging and Analysis #electronic engineering #information engineering

paper · pdf · doi:10.48550/arxiv.2308.09473

openalex publication_date 2023/08/18 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

We propose a fluid-based registration framework of medical images based on implicit neural representation. By integrating implicit neural representation and Large Deformable Diffeomorphic Metric Mapping (LDDMM), we employ a Multilayer Perceptron (MLP) as a velocity generator while optimizing velocity and image similarity. Moreover, we adopt a coarse-to-fine approach to address the challenge of deformable-based registration methods dropping into local optimal solutions, thus aiding the management of significant deformations in medical image registration. Our algorithm has been validated on a paired CT-CBCT dataset of 50 patients,taking the Dice coefficient of transferred annotations as an evaluation metric. Compared to existing methods, our approach achieves the state-of-the-art performance.

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