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Regression of carotid plaques during low density lipoprotein cholesterol elimination.

1991/08/01 by M Hennerici, Michael G. Hennerici, W Kleophas +3
Medicine · #Coronary Interventions and Diagnostics #Cerebrovascular and Carotid Artery Diseases #Antiplatelet Therapy and Cardiovascular Diseases

paper · doi:10.1161/01.str.22.8.989

Abstract

We performed serial prospective ultrasound examinations of four flat and 17 soft carotid plaques during an average of 17 months in seven patients with heterozygous hypercholesterolemia during heparin-induced extracorporeal low density lipoprotein elimination on precipitation from plasma. By means of a specially designed quantitative three-dimensional ultrasound analysis, significant plaque volume reduction could be evaluated in all subjects, along with a marked reduction of total and low density lipoprotein cholesterol and fibrinogen serum levels.

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