Molecular Labor Division: Its Cause and Consequence

2007/12/04 by Fu, Simon
#Biomolecules (q-bio.BM) #FOS: Biological sciences #Genomics (q-bio.GN) #Populations and Evolution (q-bio.PE)

paper · doi:10.48550/arxiv.0712.0462

Abstract

Both external environmental selection and internal lower-level evolution are essential for an integral picture of evolution. This paper proposes that the division of internal evolution into DNA/RNA pattern formation (genotype) and protein functional action (phenotype) resolves a universal conflict between fitness and evolvability. Specifically, this paper explains how this universal conflict drove the emergence of genotype-phenotype division, why this labor division is responsible for the extraordinary complexity of life, and how the specific ways of genotype-phenotype mapping in the labor division determine the paths and forms of evolution and development.

Related

• An Illustrated Introduction to the Basic Biological Principles
• Bring back the phenotype
• Molecular evolutionary models and mechanistic explanation
• Towards an improved understanding of molecular evolution: the relative roles of selection, drift, and everything in between
• The molecular basis of punctuated equilibria: the roles of developmental genes in stasis and speciation