The Three-Dimensional Structure of an Enzyme Molecule

1966/11/01 by D. C. Phillips, David C. Phillips · 628 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Biochemistry #Chemistry #Enzyme #Enzyme Catalysis and Immobilization #Molecule #Organic chemistry #Protein Structure and Dynamics #Various Chemistry Research Topics

paper · doi:10.1038/scientificamerican1166-78

published in Scientific American 215(5), 78 (Springer Nature)

openalex publication_date 1966/11/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/26

Cited by

• Glycosyltransferases: Structures, Functions, and Mechanisms
• Comparative analysis of permanent and transient domain–domain interactions in multi‐domain proteins
• Single-Atom Catalysts across the Periodic Table
• Compact units in proteins
• Use of Helical Wheels to Represent the Structures of Proteins and to Identify Segments with Helical Potential
• David Phillips and the origin of structural enzymology
• Binding domain [wikipedia]
• Improving protein structure similarity searches using domain boundaries based on conserved sequence information. [europepmc]
• Examining the case for the effect of barrier compression on tunneling, vibrationally enhanced catalysis, catalytic entropy and related issues. [europepmc]
• Molecular physiology of SPAK and OSR1: two Ste20-related protein kinases regulating ion transport. [europepmc]
• Binding structures of tri-N-acetyl-β-glucosamine in hen egg white lysozyme using molecular dynamics with a polarizable force field. [europepmc]
• Prediction of virulence factors using bioinformatics approaches. [europepmc]
• Characteristics and prediction of RNA structure. [europepmc]
• Dose‑dependent effect of lysozyme upon Candida albicans biofilm. [europepmc]
• Genomes, structural biology and drug discovery: combating the impacts of mutations in genetic disease and antibiotic resistance. [europepmc]
• Enhancing Evolutionary Couplings with Deep Convolutional Neural Networks. [europepmc]
• In vivo and in vitro protective effect of arginine against intestinal inflammatory response induced by Clostridium perfringens in broiler chickens. [europepmc]
• Solution of Levinthal's Paradox and a Physical Theory of Protein Folding Times. [europepmc]
• Light-controlled twister ribozyme with single-molecule detection resolves RNA function in time and space. [europepmc]
• Influenza Viruses: Harnessing the Crucial Role of the M2 Ion-Channel and Neuraminidase toward Inhibitor Design. [europepmc]
• Illuminating Disorder Induced by Glu in a Stable Arg-Anchored Transmembrane Helix. [europepmc]
• PDB-101: Educational resources supporting molecular explorations through biology and medicine. [europepmc]
• Jellyfish Bioprospecting in the Mediterranean Sea: Antioxidant and Lysozyme-Like Activities from Aurelia coerulea (Cnidaria, Scyphozoa) Extracts. [europepmc]
• A g-Type Lysozyme from Deep-Sea Hydrothermal Vent Shrimp Kills Selectively Gram-Negative Bacteria. [europepmc]
• An Overview of Antimicrobial Activity of Lysozyme and Its Functionality in Cheese. [europepmc]
• A Closed-Form, Analytical Approximation for Apparent Surface Charge and Electric Field of Molecules. [europepmc]
• Multiscale Spectral Analysis on Lysozyme Aqueous Solutions in the Presence of PolyEthyleneGlycol. [europepmc]
• Protein folding problem: enigma, paradox, solution. [europepmc]
• Formation and Applications of Typical Basic Protein-Based Heteroprotein Complex Coacervations. [europepmc]
• Surface plasmon resonance, molecular docking, and molecular dynamics simulation studies of lysozyme interaction with tannic acid. [europepmc]