2025/02/19 by Laura Leventhal, Megan Ruffley, Moisés Expósito‐Alonso · 1 voice · 5 citations
Biochemistry, Genetics and Molecular Biology · #Genetic diversity and population structure #Genomics and Phylogenetic Studies #Genetic Mapping and Diversity in Plants and Animals
paper · doi:10.1146/annurev-arplant-071123-095146
The genetics model system Arabidopsis thaliana (L.) Heynh. lives across a vast geographic range with contrasting climates, in response to which it has evolved diverse life histories and phenotypic adaptations. In the last decade, the cataloging of worldwide populations, DNA sequencing of whole genomes, and conducting of outdoor field experiments have transformed it into a powerful evolutionary ecology system to understand the genomic basis of adaptation. Here, we summarize new insights on Arabidopsis following the coordinated efforts of the 1001 Genomes Project, the latest reconstruction of biogeographic and demographic history, and the systematic genomic mapping of trait natural variation through 15 years of genome-wide association studies. We then put this in the context of local adaptation across climates by summarizing insights from 73 Arabidopsis outdoor common garden experiments conducted to date. We conclude by highlighting how molecular and genomic knowledge of adaptation can help us to understand species’ (mal)adaptation under ongoing climate change.