Long COVID science, research and policy
2024/08/01 by Ziyad Al‐Aly, Ziyad Al-Aly, Hannah Davis +5 · 5 voices · 473 citations
Medicine · Neuroscience · #Coronavirus disease 2019 (COVID-19) #Development economics #Disease #Economic growth #Economics #Global health #Health care #Infectious disease (medical specialty) #Intensive Care Unit Cognitive Disorders #Long-Term Effects of COVID-19 #Medicine #Neuroinflammation and Neurodegeneration Mechanisms #Pandemic #Political science #Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
paper · pdf · doi:10.1038/s41591-024-03173-6
published in Nature Medicine 30(8), 2148-2164 (Nature Portfolio)
openalex publication_date 2024/08/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/06
Citations
Cited by
- Dopaminergic vulnerability in long COVID: striatal PET imaging at the brain-body interface
- Sustained Reduction in Cardiopulmonary Fitness in Long COVID
- Theoretically Universal, Practically Unequal: Socio‐Economic Inequalities in Healthcare Access for Long Covid‐19 Patients in Austria
- Work ability trajectories and sick leave in individuals with post COVID-19 condition: 3-year follow-up of a population-based cohort
- Insights into Persistent SARS-CoV-2 Reservoirs in Chronic Long COVID
- Co-creating a social science research agenda for Long Covid
- Characterizing Long COVID Symptoms During Early Childhood
- Grounded in Consensus, In Step With Emerging Science: A Consensus-Anchored Multi-Corpus Clinical Chatbot for Long COVID
- Excess primary healthcare consultations in Norway in 2024 compared to pre-COVID-19-pandemic baseline trends
- PETRA: Pretrained Evolutionary Transformer for SARS-CoV-2 Mutation Prediction
- The impact of vaccination on preventing long COVID in the Omicron era: a systematic review and meta-analysis
- Preparing for the next pandemic: insights from Aotearoa New Zealand’s Covid-19 response
- Associations between different measures of SARS-CoV-2 infection status and subsequent economic inactivity: A pooled analysis of five longitudinal surveys linked to healthcare records
- Global Prevalence of Long COVID, Its Subtypes, and Risk Factors: An Updated Systematic Review and Meta-analysis
- Overview and Pathophysiology of Long COVID
- Modellierung der COVID-Infektionszahlen in Deutschland (2020–2024)
- Respiratory viral infections prime accelerated lung cancer growth
- Systemic and SARS-CoV-2 specific Immune Disturbances in Individuals With Post–COVID Syndrome
- Mapping the effectiveness and risks of GLP-1 receptor agonists
- Dysregulated NK-cell gene expression defines the enduring symptoms of long COVID-19
- Interembodiment among Long Haulers and their carers
- Proteomic signatures in cerebrospinal fluid and their clinical associations in patients with ME/CFS
- Experiences of pacing to reduce symptoms among adults living with Long COVID in Canada, Ireland, the United Kingdom and the United States
- Demo: Guide-RAG: Evidence-Driven Corpus Curation for Retrieval-Augmented Generation in Long COVID
- Intermittent fasting and a no-sugar diet for Long COVID symptoms: a randomized crossover trial
- Rates of infection with other pathogens after a positive COVID-19 test versus a negative test in US veterans (November, 2021, to December, 2023): a retrospective cohort study
- Low‐Dose naltrexone restored TRPM3 ion channel function in natural killer cells from long COVID patients
- Viral mitochondriopathy in COVID-19
- COVID time: Temporal imaginaries and pandemic materialities
- Rates of Hospitalization and Death due to COVID-19 in US Veterans With SARS-CoV-2 Infection in the XBB-, JN.1-, and KP-Predominant Eras
- HIV/AIDS and COVID-19: Shared Lessons From 2 Pandemics
- Detrimental Effects of Anti-Nucleocapsid Antibodies in SARS-CoV-2 Infection, Reinfection, and the Post-Acute Sequelae of COVID-19
- The danger theory of immunity revisited
- 2024-2025 COVID-19 Vaccine and Major Adverse Cardiovascular Events Among US Veterans
- Designing studies for post-treatment Lyme disease and other infection-associated chronic illnesses
- Structure-guided design of potent and selective covalent inhibitors of SARS-CoV-1 and SARS-CoV-2 papain-like proteases with antiviral activity
- Long Vax is delayed onset Long COVID
- Re-politicizing the WHO’s social determinants of health framework
- Modification of Social Roles Performance in People with Long COVID: A Qualitative Study
- Economic burden of long COVID: macroeconomic, cost-of-illness and microeconomic impacts
- Fasting and Caloric Restriction in Long COVID Syndrome: A Scoping Review of Interventions and Outcomes
- Blinded 2-Year Longitudinal Evaluation of SARS-CoV-2 Antigenemia in Long COVID
- An imaging flow cytometry method to study platelet-monocyte aggregates using Long COVID as a model
- Global Prevalence of Long COVID, its Subtypes and Risk factors: An Updated Systematic Review and Meta-Analysis
- Depression, but Not Fatigue, Improves as Part of Multimodal Post-COVID Rehabilitation
- The consequences of SARS-CoV-2 within-host persistence
- Early inflammatory profiling identifies patients at risk for persistent pulmonary dysfunction after COVID-19: a cohort study
- Long-term outcomes of mesenchymal stem cell therapy in severe COVID-19 patients: 3-year follow-up of a randomized, double-blind, placebo-controlled trial. [europepmc]
- A Narrative Review of the Efficacy of Long COVID Interventions on Brain Fog, Processing Speed, and Other Related Cognitive Outcomes. [europepmc]
- Episodic disability framework in the context of Long COVID: Findings from a community-engaged international qualitative study. [europepmc]
- Cumulative social disadvantage and its impact on long COVID: insights from a U.S. national survey. [europepmc]
- Translating animal models of SARS-CoV-2 infection to vascular, neurological and gastrointestinal manifestations of COVID-19. [europepmc]
- A nationwide study of risk factors for long COVID and its economic and mental health consequences in the United States. [europepmc]
- Using machine learning involving diagnoses and medications as a risk prediction tool for post-acute sequelae of COVID-19 (PASC) in primary care. [europepmc]
- Reproducibility of genetic risk factors identified for long COVID using combinatorial analysis across US and UK patient cohorts with diverse ancestries. [europepmc]
- A Direct Relationship Between 'Blood Stasis' and Fibrinaloid Microclots in Chronic, Inflammatory, and Vascular Diseases, and Some Traditional Natural Products Approaches to Treatment. [europepmc]
- Long-Term Sequelae of COVID-19: A Systematic Review and Meta-Analysis of Symptoms 3 Years Post-SARS-CoV-2 Infection. [europepmc]
- Post-COVID-19 condition: clinical phenotypes, pathophysiological mechanisms, pathology, and management strategies. [europepmc]
- A Comprehensive Scoping Review on Diet and Nutrition in Relation to Long COVID-19 Symptoms and Recovery. [europepmc]
- The Molecular Mechanisms of Cognitive Dysfunction in Long COVID: A Narrative Review. [europepmc]
- Characterizing Long COVID Symptoms During Early Childhood. [europepmc]
- Current understanding of eryptosis: mechanisms, physiological functions, role in disease, pharmacological applications, and nomenclature recommendations. [europepmc]
- Viral mitochondriopathy in COVID-19. [europepmc]
- Causes of symptoms and symptom persistence in long COVID and myalgic encephalomyelitis/chronic fatigue syndrome. [europepmc]
- Health-related quality of life in COVID-19 patients: a systematic review and meta-analysis of EQ-5D studies. [europepmc]
- Insights into Persistent SARS-CoV-2 Reservoirs in Chronic Long COVID. [europepmc]
- Vascular Complications of Long COVID-From Endothelial Dysfunction to Systemic Thrombosis: A Systematic Review. [europepmc]
- Hannah E. Davis [wikipedia]
- Lisa McCorkell [wikipedia]
- Structural MRI correlates of cognitive and neuropsychiatric symptoms in Long COVID: a pilot study. [europepmc]
- Pathophysiological, Neuropsychological, and Psychosocial Influences on Neurological and Neuropsychiatric Symptoms of Post-Acute COVID-19 Syndrome: Impacts on Recovery and Symptom Persistence. [europepmc]
- Long COVID and gut microbiome: insights into pathogenesis and therapeutics. [europepmc]
- Altered corticostriatal connectivity in long-COVID patients is associated with cognitive impairment. [europepmc]
- Hyperthermia and targeting heat shock proteins: innovative approaches for neurodegenerative disorders and Long COVID. [europepmc]
Discussions
- Wie hier schon viele geschrieben haben, betrachtest du nur einen Ausschnitt aus dem LC-Spektrum. Es wurden auch schon verschiedene Studien gepostet, aber dieser ganz wichtige Review-Artikel scheint no [bsky, 36 points, 4 comments]
- Long COVID, ME/CFS, Herz-Kreislauf-Erkrankungen, Übersterblichkeit: Die Folgen wiederholter Infektionen sind gut dokumentiert, ihre #Prävention wird jedoch aktiv verdrängt; Betroffene sind medizinisch [bsky, 15 points, 1 comments]
- Es ist wissenschaftlicher Konsens, dass Covid-19 selbst bei «milden» akuten Verläufen Schädigungen in verschiedensten Organsystemen verursachen kann und dass Infektionen in allen Altersgruppen kumulat [bsky, 4 points, 1 comments]
- 🧪 Nature Medicine
#LongCovid
Review article Received: 16 April 2024
Ziyad Al-Aly
@zalaly.bsky.social
doi.org/10.1038/s415...
“LONG COVID
Science, Research & Policy.” [bsky, 4 points, 1 comments]
- Al-Aly et al (2024) Long #COVID science, research and policy. Nature Med #OpenAccess 🧪
doi.org/10.1038/s415... [bsky, 2 points, 0 comments]