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Tailoring the Hydrophobicity of Mesoporous Organosilica for Protein Trapping and Supported Catalysis

2019/04/11 by Oriana Osta, Marianne Bombled, Osta, Oriana +11
Biochemistry, Genetics and Molecular Biology · Chemistry · Materials Science · #Chemical Synthesis and Analysis #Click Chemistry and Applications #FOS: Physical sciences #Materials Science (cond-mat.mtrl-sci) #Polymer Surface Interaction Studies

paper · pdf · doi:10.48550/arxiv.1904.05666

openalex publication_date 2019/04/11 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

We propose a method to enhance lysozyme trapping and supported-Copper catalysis when confined in organosilica materials. The direct synthesis presented here allows the control of the silica surface hydrophobicity by uniform introduction of methyl or phenyl groups. As a result, the lysozyme trapping is observed to be 3.2 times more efficient with the phenyl-functionalized material than MCM-41. For heterogeneous catalysis, Copper was immobilized on the new organosilica surface. In this case, the presence of methyl groups significantly enhanced the product yield for the catalyzed synthesis of a triazole derivative. This method opens a new route of synthesis where the material properties can be adjusted and dedicated to a specific application.

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