Neurobiology: Resetting the axon's batteries

2025/07/17 by Twiss, JL, Kalinski, AL, Sahoo, PK +2
#Axonal Transport #Axons #Nerve Regeneration #Neurobiology #Neurons

paper · doi:10.7302/26596

Abstract

Neuronal injury can cause mitochondrial damage, leading to reduced energy production, decreased Ca²⁺ storage capacity, and increased reactive oxygen species. A new study reveals a mechanism to trigger the axonal transport of previously anchored mitochondria and promote neuroprotection and axon regeneration by replacing damaged with functional mitochondria.

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