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Thematic analysis of interview data with ChatGPT: designing and testing a reliable research protocol for qualitative research

2025/06/20 by Manuel Goyanes, Carlos Lopezosa, Beatriz Jordá · 1 voice · 24 citations
Computer Science · Medicine · Social Sciences · #Artificial Intelligence in Healthcare and Education #Computational and Text Analysis Methods #Computer science #Data science #Intelligence analysis #Interpretation (philosophy) #Machine learning #Protocol (science) #Qualitative property #Qualitative research #Reflexivity #Sociology #Thematic analysis #Thematic structure #Topic Modeling

paper · pdf · doi:10.1007/s11135-025-02199-3

published in Quality & Quantity 59(6), 5491-5510 (Springer Science+Business Media)

openalex publication_date 2025/06/20 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/05

Abstract

Abstract In recent years, artificial intelligence has developed into a powerful tool for processing and generating human-like texts, unlocking innovative possibilities for quantitative and qualitative data analysis. Within qualitative research, artificial intelligence in general, and ChatGPT in particular, represent promising avenues to explore and examine textual transcriptions from interview data. This study is a step forward in this direction, advancing a reliable research protocol for using ChatGPT to conduct thematic analysis, which includes the following standard steps: (1) data preparation, (2) defining the analysis process, (3) chatbot interaction, (4) iterative process, (5) review and validation, and (6) analysis and interpretation. Results of the analysis revealed that ChatGPT may significantly facilitate qualitative data analysis exploration, especially during initial research stages and when dealing with extensive transcription material. Additionally, our protocol design is able to reliably identify different thematic patterns emerging from the text, although the granularity of the output may vary depending on the quality of the prompt and human intelligence interpretation. Accordingly, we conclude that despite its vast power, the ChatGPT model in its current state is unable to substitute the contextual insights and subtle metaphorical nuances associated with human qualitative analysis, interpretation and reflexivity.

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