2025/08/21 by Masoud Nateghi, Nateghi, Masoud, Reza Sameni +1
Engineering · Medicine · #Blood Pressure and Hypertension Studies #FOS: Electrical engineering #Hemodynamic Monitoring and Therapy #Non-Invasive Vital Sign Monitoring #Signal Processing (eess.SP) #electronic engineering #information engineering
paper · pdf · doi:10.48550/arxiv.2508.15687
openalex publication_date 2025/08/21 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
Oscillometry is the standard method for non-invasive, cuff-based blood pressure (BP) measurement, but it introduces systematic errors that may impact clinical accuracy. This study investigates the sources of these errors--primarily the limitations of oscillometry itself and respiration-induced fluctuations--using BP waveform data from the MIMIC database. Oscillometry tends to underestimate systolic BP and overestimate diastolic BP, while respiration introduces cyclical variations that further degrade measurement precision. To mitigate these effects, we propose an estimation-theoretic framework employing least squares (LS) and maximum likelihood (ML) methods for correcting both single and repeated BP measurements. LS estimation supports conventional multi-measurement averaging protocols, whereas the ML approach incorporates prior knowledge of measurement errors, offering improved performance. Our results demonstrate that leveraging statistical priors across multiple readings can enhance the accuracy of non-invasive BP monitoring, with potential implications for improving cardiovascular diagnosis and treatment.