Pharmacological inhibition of plasminogen activator inhibitor-1 prevents memory deficits and reduces neuropathology in APP/PS1 mice

2023/09/12 by Guadalupe Rodríguez, Guadalupe Rodriguez, Mesut Eren +7
Biochemistry, Genetics and Molecular Biology · Medicine · Neuroscience · #Protease and Inhibitor Mechanisms #Alzheimer's disease research and treatments #Barrier Structure and Function Studies

paper · doi:10.1007/s00213-023-06459-8

Citations

• Plasminogen activator activity is inhibited while neuroserpin is up‐regulated in the Alzheimer disease brain