2023/12/12 by Saúl Villoria-Díaz, Villoria-Díaz, Saúl, María Antonia Saornil-Álvarez +7
Biochemistry, Genetics and Molecular Biology · Medicine · #Glioma Diagnosis and Treatment #Ki-67 antigen #Medicine and health #Ocular Oncology and Treatments #Retinal Development and Disorders #astrocytes #glial fibrillary astrocytic protein #gliosis #retinal neoplasm
paper · doi:10.3205/oc000230
openalex publication_date 2023/12/12 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/19
Focal reactive nodular gliosis (FRNG) is an extremely rare benign retinal reactive astrocytic tumor that results from the proliferation of well-differentiated glial cells secondary to a variety of retinal conditions. We describe a case of this tumor in a 64-year-old male in association with a chorioretinal scar he has had since childhood. The symptom was sudden painful vision loss. In the clinical examination, iris rubeosis, posterior synechiae, cataract, vitreous haze and a suspected fundus mass were showed. B-scan ultrasonography demonstrated a retinal mass consistent with choroidal melanoma. The magnetic resonance imaging (MRI) showed a well-circumscribed mass with T1 hyperintensity and T2 hypointensity. Enucleation was performed and histopathologic and immunohistochemical studies confirmed the diagnosis of FRNG.