A Novel Group of Transcriptional Repressors in Arabidopsis

2009/03/26 by Miho Ikeda, Masaru Ohme-Takagi, Masaru Ohme‐Takagi · 260 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Arabidopsis #Biology #Computational biology #DNA #DNA-binding domain #DNA-binding protein #Gene #Gene expression #Genetics #MYB #Mutant #Photosynthetic Processes and Mechanisms #Plant Gene Expression Analysis #Plant Molecular Biology Research #Psychological repression #Repressor #Sequence motif #Transcription (linguistics) #Transcription factor

paper · pdf · doi:10.1093/pcp/pcp048

published in Plant and Cell Physiology 50(5), 970-975 (Oxford University Press)

openalex publication_date 2009/03/26 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29

Abstract

We showed previously that the ERF-associated amphiphilic repression (EAR) motif is a plant-specific repression domain that contains the conserved amino acid sequence LXLXL. In this report, we describe the identification of a novel repression domain, L/VR/KLFGVXM/V/L, which is different from known EAR motifs, in B3 DNA-binding domain transcription factors in Arabidopsis. Database analysis revealed that 29 Arabidopsis transcription factors, which included members of the RAV, ARF, Hsf and MYB families, contain the R/KLFGV conserved motif found in the novel repression domain. We demonstrated that factors that contain the R/KLFGV motif, namely, RAV1, RAV2, HsfB1 and HsfB2b, exhibited the repressive activity.

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