Tumour interstitial fluid-enriched phosphoethanolamine suppresses T cell function

2025/04/21 by Yupeng Wang, Drew N. Wilfahrt, Drew Wilfahrt +15 · 1 voice · 1 citation
Medicine · Biochemistry, Genetics and Molecular Biology · #Autophagy in Disease and Therapy #Pancreatic function and diabetes #Endoplasmic Reticulum Stress and Disease

paper · doi:10.1038/s41556-025-01650-9

Citations

• T cell metabolism drives immunity

Cited by

• The Role of One‐Carbon Metabolism in Cancer and Its Therapeutic Significance

Discussions

• 😱 Tumors sabotaging the immune system! New study in @natcellbio.nature.com shows that phosphoethanolamine in tumor interstitial fluid disables T cells by depleting diacylglycerol, crippling their sig [bsky, 46 points, 2 comments]