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Gloomy Prospects and Roller Coasters: Finding Coherence in Genome-Wide Association Studies

2020/12/01 by Carl F. Craver, Mikhail Dozmorov, Mikhail G. Dozmorov +2 · 1 citation
Biochemistry, Genetics and Molecular Biology · Psychology · #Genetic Associations and Epidemiology #Mental Health Research Topics #Cognitive Abilities and Testing

paper · doi:10.1086/710519

Abstract

We address Turkheimer’s argument that genome-wide association studies of behaviors and psychiatric traits will fail to produce coherent explanations. We distinguish two major sources of potential incoherence (heterogeneity and complexity), showing how they independently threaten coherence and considering how they are being and might better be addressed with protein and other databases and network tools.

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