Pharmacokinetic-Pharmacodynamic Modeling of Antibacterial Drugs

2013/07/01 by Elisabet I. Nielsen, Lena E. Friberg · 4 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Antibiotics Pharmacokinetics and Efficacy #Antibiotic Resistance in Bacteria #Drug Transport and Resistance Mechanisms

paper · doi:10.1124/pr.111.005769

Citations

• Trends in Risks Associated With New Drug Development: Success Rates for Investigational Drugs
• Diagnosing Model Diagnostics

Cited by

• Dose Optimization of Colistin Combinations against Carbapenem-Resistant Acinetobacter baumannii from Patients with Hospital-Acquired Pneumonia in China by Using an In Vitro Pharmacokinetic/Pharmacodynamic Model
• Mathematical modelling of synergistic triple-antibiotic therapy against carbapenem-resistant Acinetobacter baumannii at clinically achievable concentrations
• A model-based evaluation of the pharmacokinetics-pharmacodynamics (PKPD) of avibactam in combination with ceftazidime
• Simulation-based evaluation of the impact of dose fractionation study design on antibiotic PKPD analyses